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   The New England Journal of Medicine: Research & Review Articles on Disease & Clinical Practice

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   The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

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   The New England Journal of Medicine

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   Current Issue: May 23, 2013

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    The New England Journal of Medicine: Research & Review Articles on Disease & Clinical Practice Welcome Guest Renew, Subscribe or Create Account Sign In The New England Journal of Medicine Home Articles & Multimedia Issues Specialties & Topics For Authors CME AdvancedSearch original article Clinical Findings in H7N9 Virus Infection May 22, 2013 | H.-N. Gao and Others(DOI: 10.1056/NEJMoa1305584) Human infection with the novel avian-origin influenza A (H7N9) virus has aroused global concern. In this report, the clinical characteristics of 111 laboratory-confirmed cases in China are presented. correspondence Live-Animal Markets and Influenza A (H7N9) Virus Infection May 22, 2013 | C. Bao and Others(DOI: 10.1056/NEJMc1306100) More on Influenza A (H7N9) original article Low-Dose CT Screening for Lung Cancer May 23, 2013 | The National Lung Screening Trial Research Team In participants who underwent initial screening in the National Lung Cancer Screening Trial, low-dose CT scanning showed positive results three times as frequently as did chest radiography (27% vs. 9%) and detected more than twice as many stage I cancers (158 vs. 70). CME case challenge A Woman with Diabetes Mellitus and Fatigue May 22, 2013 A 56-year-old woman with diabetes mellitus was admitted to the hospital because of hyperglycemia and chest pain. Read the full case description for case 17-2013. What is the diagnosis? What diagnostic test is indicated? Vote and comment. Find the answers in the full text of the case, to be published on May 30. Comments Poll original article Bronchiectasis in Children with Cystic Fibrosis May 23, 2013 | P.D. Sly and Others Published Online: May 21, 2013 Bronchiectasis causes substantial morbidity in patients with cystic fibrosis. In this study, children were followed from diagnosis until 3 years of age. Neutrophil elastase activity in the lung at 3 months of age was associated with persistent bronchiectasis. CME Comments Related Editorial perspective The GDP and Health Care Spending May 22, 2013 | V.R. Fuchs(DOI: 10.1056/NEJMp1305298) perspective Under the Medical Tent at the Boston Marathon May 23, 2013 | S. Jangi Published Online: April 23, 2013 Free Full Text Comments Featured Multimedia Acute Myeloid Leukemia The Cancer Genome Atlas Research Network Video Preparing for Mass Casualties A.L. Kellermann Audio Interview Current Issue: May 23, 2013 Weekly Audio Summary Listen Download Browse Past Issues original articles Risk Factors for Bronchiectasis in Children with Cystic Fibrosis P.D. Sly and Others Published Online: May 21, 2013 CME Comments Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ M.D. Shirley and Others Published Online: May 8, 2013 Results of Initial Low-Dose Computed Tomographic Screening for Lung Cancer The National Lung Screening Trial Research Team CME Ataxia, Dementia, and Hypogonadotropism Caused by Disordered Ubiquitination D.H. Margolin and Others Published Online: May 8, 2013 review article Mechanisms of Disease: Mechanisms of Acute Coronary Syndromes and Their Implications for Therapy P. Libby images in clinical medicine Mastoiditis Y.-J. Liao and T.-C. Liu Free Full Text Dystrophic Calcinosis Cutis N. Aggarwal and S. Shrestha Free Full Text case records of the massachusettsgeneral hospital Case 16-2013: A 12-Year-Old Girl with Irritability, Hypersomnia, and Somatic Symptoms S.L. Bender, N.A. Sherry, and R. Masia CME editorial Identifying the Origins of Cystic Fibrosis Lung Disease S.D. Davis and T. Ferkol Published Online: May 21, 2013 sounding board Phasing Out Fee-for-Service Payment S.A. Schroeder and W. Frist Published Online: March 27, 2013 Free Full Text Comments Public Health Approach to the Prevention of Gun Violence D. Hemenway and M. Miller Published Online: April 12, 2013 Perspective Under the Medical Tent at the Boston Marathon S. Jangi Published Online: April 23, 2013 Free Full Text Comments Lessons from Boston A.L. Kellermann and K. Peleg Published Online: April 24, 2013 Free Full Text Audio Interview Comments Be Prepared — The Boston Marathon and Mass-Casualty Events P.D. Biddinger and Others Published Online: May 1, 2013 Free Full Text Comments We Fight Like We Train E. Goralnick and J. Gates Published Online: May 1, 2013 Free Full Text Comments Saving Specimens after Sandy S. Zolla-Pazner Published Online: May 8, 2013 Free Full Text Correspondence Short-Course Antiretroviral Therapy in Primary HIV Infection Neurostimulation for Parkinson’s Disease with Early Motor Complications Esophageal Sphincter Device for Gastroesophageal Reflux Disease Vitamin B12 Deficiency Transient Sunitinib Resistance in Gastrointestinal Stromal Tumors Bioresorbable Airway Splint Created with a Three-Dimensional Printer Corrections No corrections published in this issue original article Clinical Findings in 111 Cases of Influenza A (H7N9) Virus Infection May 22, 2013 | H.-N. Gao and Others(DOI: 10.1056/NEJMoa1305584) perspective The Gross Domestic Product and Health Care Spending May 22, 2013 | V.R. Fuchs(DOI: 10.1056/NEJMp1305298) More Online First Articles --> Image Challenge What is the diagnosis? More Image Challenges Image of the Week Postauricular Swelling A 60-year-old man presented with hearing loss and otorrhea. Recent Featured Images Trends Most Viewed (Last Week) Original Article Prone Positioning in Severe Acute Respiratory Distress Syndrome May 20, 2013 | C. Guérin and Others Original Article A Randomized Trial of Nighttime Physician Staffing in an Intensive Care Unit May 20, 2013 | M.P. Kerlin and Others Review Article Current and Future Therapies for Hepatitis C Virus Infection May 16, 2013 | T.J. Liang and M.G. Ghany More Trends Content: Home Current Issue Articles Issue Index Specialties & Topics Multimedia & Images Archive 1812-1989 Information For: Authors Reviewers Subscribers Institutions Media Advertisers Services: Subscribe Renew Pay Bill Activate Subscription Create or Manage Account Alerts RSS & Podcasts Submit a Manuscript Mobile Resources: Physician Jobs Reprints Permissions Medical Meetings Conventions FAQs Journal Watch Help Contact Us NEJM: About Product Information Editors & Publishers 200th Anniversary Terms of Use Privacy Policy Copyright Advertising Policies NEJM Group CME: Weekly CME Program Browse Weekly Exams Your CME Activity Purchase Exams Review CME Program Follow us Article Category Research Reviews Clinical Cases Perspective Commentary Other Browse all articles Multimedia Videos in Clinical Medicine Images in Clinical Medicine Interactive Medical Cases Weekly Audio Summaries Browse all multimedia This Week Last Week Browse full index Selected Specialties Cardiology Endocrinology Gastroenterology Genetics Hematology/Oncology Infectious Disease Nephrology Neurology/Neurosurgery Obstetrics/Gynecology Pediatrics Primary Care/Hospitalist Pulmonary/Critical Care Surgery Browse all Specialties & Topics Featured Topics Clinical Practice Center Health Policy and Reform Medicine and Society Global Health Influenza A (H7N9) Author Center Submit a Manuscript or Letter Track a Manuscript Help Copyright © 2013 Massachusetts Medical Society. 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